Main Article Content


A specific, precise, accurate, reproducible and robust method was developed for the estimation of Alfuzosin Hcl by UV Spectroscopy using pH 7.4 phosphate buffer as a solvent. Absorption spectrum was obtained by scanning from 200-400nm and the maximum absorbance was found at 350nm. Then the method was optimized and validated with various validation parameters as per ICH guidelines. From the linearity studies correlation coefficient was found to be 0.9995. From precision and intermediate precision studies %RSD was found to be 0.573 and 0.097 respectively. Assay was conducted by using marketed formulation of AlfuzosinHcl and the % purity was found to be 98.5%. Hence the method was suitable for the estimation of AlfuzosinHcl by UV Spectroscopy. carried out at three different levels i.e. at 80%, 100% and 120%. The method was validated statistically.

Article Details

How to Cite
A. Raja Reddy, S. Harshitha, & T. Ramara Rao. (2024). Analytical Method Development And Validation Of Alfuzosin HCL By UV- Spectrophotometer. International Journal of Intellectual Advancements and Research in Engineering Computations, 12(2), 12–17. Retrieved from