https://ijiarec.com/ijiarec <p>IJIAREC- International Journal of Intellectual Advancements and Research in Engineering Computations is a leading international journal for publication of new ideas, the state of the art research results and fundamental advances in all aspects of computer science and engineering. IJIAREC is a scholarly open access, peer reviewed international journal with a primary objective to provide the academic community and industry for the submission of half of original research and applications related to Computer Science and Engineering.</p> Prof.Dr.N.Sriram en-US International journal of intellectual advancements and research in engineering computations 2348-2079 https://ijiarec.com/ijiarec/article/view/1793 <p>Epilepsy (EP) is a ceaseless issue in modern nations because of tobacco smoking, hot food varieties, way of life changes, albuminuria, ulcers, IBS, skin rashes and deferred wounds. Many of these contemporary synthetic drugs were treated through EP-associated disease conditions to expel less therapeutic efficacy, unwanted effects and unknowing unwanted effects. Our present survey found to estimate the various parameters of antiepileptic drug-consuming patients in various zones of Kerala. The literature surveyed based on a selected cohort was used. In our study, 1500 epileptic patient details were collected&nbsp; The present study aimed to determine the pattern of prescription of antiepileptic drugs (AEDs) in a cohort of patients with epilepsy (PWE) attending a tertiary care centre in the Kerala zone. The related illnesses condition results communicated that the EP-related infections pervasiveness was low (502 Numbers and 51.1%) contrasted with Non-related sicknesses (300 Numbers and 57.9 %). The discoveries of extreme EP Patients' pervasiveness were more (182 Numbers and 18.5%) when contrasted with serious EP patients (18 Numbers and 3.4 %) Polytherapy is a very common practice in our tertiary care centre. Sodium VPA, a highly prescribed AED, results in good control of generalized seizures, whereas focal seizures are well controlled by CBZ alone as well as in combination. The present study highlights the commonly prescribed combinations of AEDs resulting in the control of different types of seizures.</p> Muhammad Ashraf Vattikuth G. Nagaraja perumal Copyright (c) 2024 2024-04-03 2024-04-03 12 2 1 11 https://ijiarec.com/ijiarec/article/view/1794 <p>A specific, precise, accurate, reproducible and robust method was developed for the estimation of Alfuzosin Hcl by UV Spectroscopy using pH 7.4 phosphate buffer as a solvent. Absorption spectrum was obtained by scanning from 200-400nm and the maximum absorbance was found at 350nm. Then the method was optimized and validated with various validation parameters as per ICH guidelines. From the linearity studies correlation coefficient was found to be 0.9995. From precision and intermediate precision studies %RSD was found to be 0.573 and 0.097 respectively. Assay was conducted by using marketed formulation of AlfuzosinHcl and the % purity was found to be 98.5%. Hence the method was suitable for the estimation of AlfuzosinHcl by UV Spectroscopy. carried out at three different levels i.e. at 80%, 100% and 120%. The method was validated statistically.</p> A. Raja Reddy S. Harshitha T. Ramara Rao Copyright (c) 2024 2024-04-03 2024-04-03 12 2 12 17